Dracorhodin Perchlorate
MedKoo试剂Dracorhodin Perchlorate(CAS125536-25-6)
产品品牌:MedKoo
产品货号:573990
产品规格:25.0mg; 50.0mg; 100.0mg; 250.0mg
产品价格:咨询
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产品介绍
产品简介:
Dracorhodin Perchlorate是一种促凋亡化合物,是一种花青素龙胆素的合成类似物。当浓度为40 μM和80 μM时,可诱导U87MG和T98G胶质瘤细胞在G0/G1期细胞周期阻滞和凋亡。它还增加了体外胶质瘤细胞中p53、p21、Bim和Bax的水平,并降低了Bcl-2的水平。高氯酸龙胆素对U937、A375-S2和MCF-7细胞具有浓度依赖性的细胞毒性。它对HeLa细胞也有细胞毒性,这种作用可以被Ac-YVAD-CMK、Z-DEVD-FMK、Z-IETD-FMK和Z-LEHD-FMK逆转,它们分别是caspase-1、-3、-8和-9的抑制剂。
产品属性:
Name: Dracorhodin Perchlorate
CAS#: 125536-25-6
Chemical Formula: C17H15ClO7
Exact Mass: 366.0506
Molecular Weight: 366.75
Elemental Analysis: C, 55.67; H, 4.12; Cl, 9.67; O, 30.54
Synonym: Dracorhodin Perchlorate
IUPAC/Chemical Name: 7-hydroxy-5-methoxy-6-methyl-2-phenyl-1-benzopyrylium, monoperchlorate
InChi Key: KRTYZFUODYMZPG-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H14O3.ClHO4/c1-11-14(18)10-16-13(17(11)19-2)8-9-15(20-16)12-6-4-3-5-7-12;2-1(3,4)5/h3-10H,1-2H3;(H,2,3,4,5)
SMILES Code: OC1=C(C)C(OC)=C(C=CC(C2=CC=CC=C2)=[O+]3)C3=C1.O=Cl([O-])(=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购:
货号 | 产品名称 | 规格 |
573990 |
Dracorhodin Perchlorate | 25.0mg 50.0mg 100.0mg 250.0mg |