2'-Deoxyinosine(CAS#:890-38-0)
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产品介绍
Description: 2’-Deoxyinosine is the nucleoside form of hypoxanthine. It is a product of DNA damage that is formed from 2’-deoxyadenosine by adenosine deaminase or reactive nitrogen species. 2’-deoxyinosine enhances apoptosis induced by 5-fluorouracil in HT-29 and SW620 cancer cells. It also enhances 5-FU-induced tumor growth suppression in an SW620 mouse xenograft model when administered at a dose of 1.6 g/kg twice per day.
Name: 2'-Deoxyinosine
CAS#: 890-38-0
Chemical Formula: C10H12N4O4
Exact Mass: 252.0859
Molecular Weight: 252.23
Elemental Analysis: C, 47.62; H, 4.80; N, 22.21; O, 25.37
Synonym: 2'-Deoxyinosine;
IUPAC/Chemical Name: 9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
InChi Key: VGONTNSXDCQUGY-RRKCRQDMSA-N
InChi Code: InChI=1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1
SMILES Code: [H][C@@]1(N2C(N([H])C=NC3=O)=C3N=C2)O[C@H](CO)[C@@H](O)C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
