7-Xylosyltaxol
MedKoo试剂7-Xylosyltaxol(CAS90332-66-4)
产品品牌:MedKoo
产品货号:463775
产品规格:1.0mg; 5.0mg;
产品价格:咨询
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产品介绍
产品简介:
7-Xylosyltaxol是紫杉醇的一种紫杉烷和衍生物,具有微管干扰和抗癌活性。在无细胞实验中,它诱导猪脑和绒泡菌微管的分解。7-Xylosyltaxol对A549、MCF-7、A2780、HCT-8和SW480癌细胞的增殖抑制作用,IC50值分别为0.39、0.16、0.85、5.9和5.6µM。
产品属性:
Chemical Formula: C52H59NO18
Exact Mass: 985.3732
Molecular Weight: 986.033
Elemental Analysis: C, 63.34; H, 6.03; N, 1.42; O, 29.21
Synonym: 7-Xylosyltaxol; 7 Xylosyltaxol;
IUPAC/Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate
InChi Key: ZVEGOBHUZTXSFK-TZIKQHFSSA-N
InChi Code: InChI=1S/C52H59NO18/c1-26-33(68-47(63)39(58)37(29-16-10-7-11-17-29)53-45(61)30-18-12-8-13-19-30)23-52(64)44(70-46(62)31-20-14-9-15-21-31)42-50(6,43(60)41(67-27(2)54)36(26)49(52,4)5)34(22-35-51(42,25-66-35)71-28(3)55)69-48-40(59)38(57)32(56)24-65-48/h7-21,32-35,37-42,44,48,56-59,64H,22-25H2,1-6H3,(H,53,61)/t32-,33+,34+,35-,37+,38+,39-,40-,41-,42+,44+,48+,50-,51+,52-/m1/s1
SMILES Code: C[C@@]1([C@@]([H])([C@@](CO2)(OC(C)=O)[C@]2(C[C@@H]1O[C@@]([H])([C@H](O)[C@H]3O)OC[C@H]3O)[H])[C@@H]4OC(C5=CC=CC=C5)=O)C([C@H](OC(C)=O)C6=C([C@H](C[C@@]4(C6(C)C)O)OC([C@@H]([C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)O)=O)C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购:
货号 | 产品名称 | 规格 |
463775 | 7-Xylosyltaxol | 1.0mg 5.0mg |