8-hydroxy Efavirenz
MedKoo试剂8-hydroxy Efavirenz(CAS205754-33-2)
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产品介绍
产品简介：
8-hydroxy Efavirenz是非核苷类逆转录酶抑制剂Efavirenz的主要氧化代谢物。当efavirenz被细胞色素P450 (CYP)异构体CYP2B6代谢时形成8-hydroxy Efavirenz。它能诱导大鼠海马原代神经元凋亡和树突棘丢失。
产品属性：
Chemical Formula: C14H9ClF3NO3
Exact Mass: 331.0223
Molecular Weight: 331.68
Elemental Analysis: C, 50.70; H, 2.74; Cl, 10.69; F, 17.18; N, 4.22; O, 14.47
Synonym: 8-hydroxy Efavirenz
IUPAC/Chemical Name: (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
InChi Key: OOVOMPCQLMFEDT-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21)
SMILES Code: ClC1=CC(O)=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购：
货号 | 产品名称 | 规格 |
574226 | 8-hydroxy Efavirenz | 1.0mg |
