11-cis Retinol (CAS:22737-96-8)
产品介绍
Description: 11-cis Retinol is an isomer of vitamin A. It is formed from vitamin A, via a trans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle. 11-cis Retinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells. It promotes pigment formation in cone, but not rod, photoreceptors.
Name: 11-cis Retinol
Chemical Formula: C20H30O
Exact Mass:286.2297
Molecular Weight: 286.459
Elemental Analysis:C, 83.86; H, 10.56; O, 5.59
Synonym: 11-cis Retinol; 11 cis-Retinol; 11 cis Retinol; 11-cis-Retinol;
IUPAC/Chemical Name: (2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
InChi Key: FPIPGXGPPPQFEQ-IOUUIBBYSA-N
InChi Code: InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6-,12-11+,16-8+,17-13+
SMILES Code: OC/C=C(/C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001