Product Description：Inhibin B is a dimeric hormone that is composed of alpha (α) and beta B (βB) subunits. The free alpha subunits usually do not have any physiological effect. Therefore, the bioactivity of the inhibins depends on the formation of a dimeric α-β structure, and only dimeric forms of inhibins are biologically active. Inhibins are protein hormones secreted by granulosa cells of the ovary in the female and sertoli cells of the testis in the male. They selectively suppress the secretion of pituitary follicle stimulating hormone (FSH) and also have local paracrine actions in the gonads. Inhibin B levels have been reported in sertoli cell function (potential marker for spermatogenesis and testicular function), ovarian reserve and granulosa cell tumors.
Regulatory Status：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Packaging：96 well microtiter
Detection：HRP-based ELISA, colorimetric detection by dual wavelength absorbance at 450 nm and 630 nm as reference filter
Dynamic Range：6, 12.7-1390 pg/mL
Limit of Detection：1.6 pg/mL
Assay Time：3.5 hours
Shelf Life：24 months