Dolasetron(CAS#:115956-12-2)
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产品规格：5.0mg; 10.0mg; 25.0mg
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产品介绍
Description: Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
Name: Dolasetron
CAS#: 115956-12-2
Chemical Formula: C19H20N2O3
Exact Mass: 324.1474
Molecular Weight: 324.3737
Elemental Analysis: C, 70.35; H, 6.21; N, 8.64; O, 14.80
Synonym: HSDB 7565; HSDB7565; HSDB-7565; Dolasetron; Dolasetronum
IUPAC/Chemical Name: (6R)-3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
InChi Key: UKTAZPQNNNJVKR-DBBXXEFVSA-N
InChi Code: InChI=1S/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2/t11?,12-,13?,14?/m1/s1
SMILES Code: O=C(C1=CNC2=C1C=CC=C2)OC(CC3N4C5)C[C@@]4([H])CC(C3)C5=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
