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(15R)-PGE2 #38873-82-4

产品品牌:MedKoo
产品货号:38873-82-4
产品规格:1.0mg
产品价格:咨询
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产品介绍

Description:15(R)-Prostaglandin E2 is the C-15 epimer of the naturally occurring 15(S)-PGE2 (sc-201225) isomer; the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects, but this compound shows much lower potency in most biological assays; however acid catalyzed epimerization can convert this compound to the active form - 15(S)-Prostaglandin E2.

Name (15R)-PGE2

Chemical Formula C20H32O5
Exact Mass352.225
Molecular Weight 352.47
Elemental AnalysisC, 68.15; H, 9.15; O, 22.70

Synonym(15R)-PGE2; 15(R)-Prostaglandin E2

IUPAC/Chemical Name (Z)-7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid

InChi Key XEYBRNLFEZDVAW-GKEZHNTDSA-N

InChi Code InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,19-/m1/s1

SMILES Code O[C@@H]1CC([C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@H](O)CCCCC)=O

Appearance Solid powder

Purity >98% (or refer to the Certificate of Analysis)

Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

SolubilitySoluble in DMSO

Shelf Life >3 years if stored properly

Drug Formulation This drug may be formulated in DMSO

Stock Solution Storage 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code 2934.99.9001