(15R)-PGE2 #38873-82-4
产品介绍
Description:15(R)-Prostaglandin E2 is the C-15 epimer of the naturally occurring 15(S)-PGE2 (sc-201225) isomer; the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects, but this compound shows much lower potency in most biological assays; however acid catalyzed epimerization can convert this compound to the active form - 15(S)-Prostaglandin E2.
Name: (15R)-PGE2
Chemical Formula: C20H32O5
Exact Mass:352.225
Molecular Weight: 352.47
Elemental Analysis:C, 68.15; H, 9.15; O, 22.70
Synonym:(15R)-PGE2; 15(R)-Prostaglandin E2
IUPAC/Chemical Name: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid
InChi Key: XEYBRNLFEZDVAW-GKEZHNTDSA-N
InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,19-/m1/s1
SMILES Code: O[C@@H]1CC([C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@H](O)CCCCC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
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