Disogluside(CAS#:14144-06-0)
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热线电话: 400-888-3135
产品介绍
Description: Disogluside is an active ingredient isolated from Dioscorea nipponica Makino. Trillin reduces liver chronic inflammation and fibrosis in carbon tetrachloride (CCl4) induced liver injury in mice. Trillin exhibited protective effect on LPS-induced ALI by the regulations of related inflammatory events via the activations of Nrf2, HO-1 and NF-κB pathway. Trillin has being shown to exert protective effects against hyperlipidemia and oxidative stress. Trillin induced multinucleation in HL-60, NB4 and K562 cells, indicating it could induce mitotic arrest in these leukemia cells.
Name: Disogluside
CAS#: 14144-06-0
Chemical Formula: C33H52O8
Exact Mass: 576.3662
Molecular Weight: 576.77
Elemental Analysis: C, 68.72; H, 9.09; O, 22.19
Synonym: Disogluside; Trillin
IUPAC/Chemical Name: (25R)-3beta-(beta-D-Glucopyranosyloxy)spirost-5-ene
InChi Key: WXMARHKAXWRNDM-GAMIEDRGSA-N
InChi Code: InChI=1S/C33H52O8/c1-17-7-12-33(38-16-17)18(2)26-24(41-33)14-23-21-6-5-19-13-20(8-10-31(19,3)22(21)9-11-32(23,26)4)39-30-29(37)28(36)27(35)25(15-34)40-30/h5,17-18,20-30,34-37H,6-16H2,1-4H3/t17-,18+,20+,21-,22+,23+,24+,25-,26+,27-,28+,29-,30-,31+,32+,33-/m1/s1
SMILES Code: [H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O[C@H]7[C@@H]([C@H]([C@@H]([C@@H](CO)O7)O)O)O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
