Donepezil HCl(CAS#:120011-70-3 (HCl))
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产品规格：200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g; 10.0g
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产品介绍
Description: Donepezil HCl is a GSK3 and AChE inhibitor and potential σ1 receptor agonist used to treat Alzheimer's disease. It also improves learning and memory, downregulates expression of NR1 subuinit of NMDA receptors, decreases left ventricular end diastolic pressure, and increases left ventricular contractility.
Name: Donepezil HCl
CAS#: 120011-70-3 (HCl)
Chemical Formula: C24H30ClNO3
Exact Mass:
Molecular Weight: 415.95
Elemental Analysis: C, 69.30; H, 7.27; Cl, 8.52; N, 3.37; O, 11.54
Synonym: Aricept; E-2020; E2020; E 2020; Donepezil HCl
IUPAC/Chemical Name: 2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride
InChi Key: XWAIAVWHZJNZQQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
SMILES Code: O=C1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2933.39.9100
