D-Kynurenine(CAS#:13441-51-5)
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产品介绍
Description: D-Kynurenine is an antagonist of hydroxycarboxylic acid receptor 3 HCA3/GPR109B and a metabolite of D-tryptophan. It increases levels of intracellular calcium and decreases forskolin-stimulated production of cAMP in CHO cells expressing human HCA3/GPR109B. D-Kynurenine increases expression of vimentin and decreases expression of E-cadherin in 95D lung cancer cells. It has been used as a substrate in fluorometric assays for D-amino acid oxidase activity.
Name: D-Kynurenine
CAS#: 13441-51-5
Chemical Formula: C10H12N2O3
Exact Mass: 208.0848
Molecular Weight: 208.22
Elemental Analysis: C, 57.69; H, 5.81; N, 13.45; O, 23.05
Synonym: D-Kynurenine
IUPAC/Chemical Name: (R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
InChi Key: YGPSJZOEDVAXAB-MRVPVSSYSA-N
InChi Code: InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1
SMILES Code: NC1=C(C(C[C@@H](N)C(O)=O)=O)C=CC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
