A 1070722
MedKoo试剂A 1070722(CAS1384424-80-9)
产品品牌:MedKoo
产品货号:558767
产品规格:10.0mg; 50.0mg;
产品价格:咨询
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产品介绍
产品简介:
强效糖原合成酶激酶3 (GSK-3)抑制剂(Ki = 0.6 nM, GSK-3α和GSK-3β)。对GSK-3显示高选择性(> - 50倍),超过一组其他激酶测试,包括CDK家族成员。在体外降低微管相关蛋白Tau的磷酸化;保护大鼠初级皮层神经元免受β淀粉样蛋白和谷氨酸的攻击。大脑渗透。
产品属性:
Chemical Formula: C17H13F3N4O2
Exact Mass: 362.1
Molecular Weight: 362.31
Elemental Analysis: C, 56.36; H, 3.62; F, 15.73; N, 15.46; O, 8.83
Synonym: 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea
IUPAC/Chemical Name: 1-(7-methoxyquinolin-4-yl)-3-(6-(trifluoromethyl)pyridin-2-yl)urea
InChi Key: VQPBIJGXSXEOCU-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)
SMILES Code: O=C(NC3=NC(C(F)(F)F)=CC=C3)NC2=CC=NC1=CC(OC)=CC=C12
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
产品订购:
货号 | 产品名称 | 规格 |
574679 |
DPP-IV-IN-2 | 1.0mg 5.0mg 10.0mg |