产品简介：This mouse IgG1 monoclonal antibody was generated against human E-cadherin (partial, amino acids 155-707) and recognizes human and dog cadherin-1 (CDH1).

产品优势：Reacts with human and dog CDH1.Can bind human E-cadherin protein on the cell surface and activate the protein to stimulate strong cell-cell adhesion between tumor cells. Suitable for ELISA and Immunofluorescence, Immunocytochemistry, Western Blot and Immunoprecipitation applications.Cadherin-1 is a member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Mutations in this gene have been shown to associated with gastric, breast, colorectal, thyroid, and ovarian cancers.

抗原：Cadherin-1.

亚型：IgG1.

克隆名称：19A11.

适应物种：Human and dog.

免疫原：Human E-cadherin (partial, amino acids 155-707).

免疫物种：Mouse.

应用范围：WB, ELISA, IF(ICC), IP.

储存：-20C.