产品简介：This mouse IgG2a monoclonal antibody (clone AK1G4) was generated against purified recombinant human Osteopontin (OPN) and is specific for the C-terminal region of human OPN (epitope: aa 13-16).Osteopontin (OPN, also designated Bone Sialoprotein 1, Urinary Stone Protein, spp-1, eta-1, nephropontin, uropontin) is a phosphoglycoprotein synthesized in a variety of tissues and cells. It was originally identified as a bone matrix protein and subsequently as a cytokine produced by various immune and transformed cell lines. OPN is a biomarker for various types of cancers and inflammatory diseases. Excessive or dysregulated OPN expression has been linked to the pathogenesis of both autoimmune disorders such as multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, atherosclerosis and other inflammatory diseases including cardiovascular disease, chronic obstructive pulmonary disease, inflammatory bowel disease, liver disease and asthma.

抗原：Osteopontin (OPN) protein.

亚型：IgG1, kappa.

克隆名称：2A1.

适应物种：Human and mouse.

免疫原：recombinant histidine-tagged human OPN (prepared in E. coli and purified on a nickel column).

免疫物种：Mouse.

应用范围：WB, ELISA, IP, IF, IHC.

储存：-20C.